Tucked along one of the most desirable tree-lined streets in Sherman Oaks' coveted M Street neighborhood, 4521 Mary Ellen Avenue is a newly constructed architectural residence designed by DesignBuildLA. The home is defined by timeless materials, restrained detailing, and exceptional craftsmanship. The exterior introduces the home's material palette with smooth stucco, honed travertine brick, and a custom White Oak entry door. Inside, wide plank White Oak floors, hand-applied Moroccan clay walls, and custom millwork establish a cohesive palette carried throughout the home. Gentle curves woven into the cabinetry and built-ins soften the clean architectural lines while adding warmth, character, and function. The kitchen is anchored by a dramatic 15-foot island wrapped in Calacatta marble and appointed with custom cabinetry, Allied Maker lighting, and a complete Thermador appliance suite with built-in refrigeration. A fully equipped butler's pantry with double wall ovens, an integrated coffee system, additional prep space, and abundant storage allows the main kitchen to remain effortless when hosting. A versatile recreation room offers the perfect space for a movie theater, game room, or lounge, complete with a custom bar featuring Ceppo stone countertops and green Moroccan clay walls, creating a bold yet sophisticated setting for entertaining. The primary suite offers a private retreat with a spa-inspired bath featuring dual showers, quartzite stone, limestone flooring, plaster walls, a custom curved White Oak vanity, and a freestanding soaking tub. Secondary bathrooms continue the same level of craftsmanship with natural stone countertops, Zia tile, Eco Outdoor travertine tile, and thoughtfully selected fixtures, while the powder room makes its own statement with a striking Green Fusion quartzite slab set against rich plaster walls. Designed for seamless indoor-outdoor living, the backyard centers around a heated pool and spa, a covered patio with built-in speakers, and professionally designed landscaping by Studio Elico. Mature African Sumac, California Pepper, and Weeping Willow trees create a landscape that feels established and private, an uncommon quality for a newly built residence. Additional highlights include designer lighting, custom millwork throughout, premium natural materials, Control4 smart home system, and a floor plan that thoughtfully balances expansive entertaining spaces with comfortable daily living.